diff --git a/docker/api/container.py b/docker/api/container.py
index 85e5e90a..97b54059 100644
--- a/docker/api/container.py
+++ b/docker/api/container.py
@@ -479,6 +479,8 @@ class ContainerApiMixin(object):
             cpu_shares (int): CPU shares (relative weight).
             cpuset_cpus (str): CPUs in which to allow execution (``0-3``,
                 ``0,1``).
+            cpuset_mems (str): Memory nodes (MEMs) in which to allow execution
+                (``0-3``, ``0,1``). Only effective on NUMA systems.
             device_read_bps: Limit read rate (bytes per second) from a device
                 in the form of: `[{"Path": "device_path", "Rate": rate}]`
             device_read_iops: Limit read rate (IO per second) from a device.
diff --git a/docker/models/containers.py b/docker/models/containers.py
index f1c0fd26..2213583a 100644
--- a/docker/models/containers.py
+++ b/docker/models/containers.py
@@ -483,6 +483,8 @@ class ContainerCollection(Collection):
             cpu_shares (int): CPU shares (relative weight).
             cpuset_cpus (str): CPUs in which to allow execution (``0-3``,
                 ``0,1``).
+            cpuset_mems (str): Memory nodes (MEMs) in which to allow execution
+                (``0-3``, ``0,1``). Only effective on NUMA systems.
             detach (bool): Run container in the background and return a
                 :py:class:`Container` object.
             device_read_bps: Limit read rate (bytes per second) from a device
@@ -829,6 +831,7 @@ RUN_HOST_CONFIG_KWARGS = [
     'cpu_quota',
     'cpu_shares',
     'cpuset_cpus',
+    'cpuset_mems',
     'device_read_bps',
     'device_read_iops',
     'device_write_bps',
diff --git a/docker/types/containers.py b/docker/types/containers.py
index 9f1a04d1..ad162555 100644
--- a/docker/types/containers.py
+++ b/docker/types/containers.py
@@ -119,7 +119,8 @@ class HostConfig(dict):
                  cpuset_cpus=None, userns_mode=None, pids_limit=None,
                  isolation=None, auto_remove=False, storage_opt=None,
                  init=None, init_path=None, volume_driver=None,
-                 cpu_count=None, cpu_percent=None, nano_cpus=None):
+                 cpu_count=None, cpu_percent=None, nano_cpus=None,
+                 cpuset_mems=None):
 
         if mem_limit is not None:
             self['Memory'] = parse_bytes(mem_limit)
@@ -328,6 +329,16 @@ class HostConfig(dict):
 
             self['CpuSetCpus'] = cpuset_cpus
 
+        if cpuset_mems:
+            if version_lt(version, '1.19'):
+                raise host_config_version_error('cpuset_mems', '1.19')
+
+            if not isinstance(cpuset_mems, str):
+                raise host_config_type_error(
+                    'cpuset_mems', cpuset_mems, 'str'
+                )
+            self['CpusetMems'] = cpuset_mems
+
         if blkio_weight:
             if not isinstance(blkio_weight, int):
                 raise host_config_type_error(
diff --git a/tests/unit/api_container_test.py b/tests/unit/api_container_test.py
index 901934ee..39df2939 100644
--- a/tests/unit/api_container_test.py
+++ b/tests/unit/api_container_test.py
@@ -338,6 +338,33 @@ class CreateContainerTest(BaseAPIClientTest):
         self.assertEqual(args[1]['headers'],
                          {'Content-Type': 'application/json'})
 
+    @requires_api_version('1.19')
+    def test_create_container_with_host_config_cpuset_mems(self):
+        self.client.create_container(
+            'busybox', 'ls', host_config=self.client.create_host_config(
+                cpuset_mems='0'
+            )
+        )
+
+        args = fake_request.call_args
+        self.assertEqual(args[0][1],
+                         url_prefix + 'containers/create')
+
+        self.assertEqual(json.loads(args[1]['data']),
+                         json.loads('''
+                            {"Tty": false, "Image": "busybox",
+                             "Cmd": ["ls"], "AttachStdin": false,
+                             "AttachStderr": true,
+                             "AttachStdout": true, "OpenStdin": false,
+                             "StdinOnce": false,
+                             "NetworkDisabled": false,
+                             "HostConfig": {
+                                "CpusetMems": "0",
+                                "NetworkMode": "default"
+                             }}'''))
+        self.assertEqual(args[1]['headers'],
+                         {'Content-Type': 'application/json'})
+
     def test_create_container_with_cgroup_parent(self):
         self.client.create_container(
             'busybox', 'ls', host_config=self.client.create_host_config(