diff --git a/docker/constants.py b/docker/constants.py
index 0e39dc29..1e001fd3 100644
--- a/docker/constants.py
+++ b/docker/constants.py
@@ -1,3 +1,4 @@
+import os
 import sys
 
 from .version import __version__
@@ -11,7 +12,14 @@ CONTAINER_LIMITS_KEYS = [
 ]
 
 DEFAULT_HTTP_HOST = "127.0.0.1"
-DEFAULT_UNIX_SOCKET = "http+unix:///var/run/docker.sock"
+
+# Check for OrbStack socket first, fall back to standard Docker socket
+ORBSTACK_SOCKET = os.path.expanduser("~/.orbstack/run/docker.sock")
+if os.path.exists(ORBSTACK_SOCKET):
+    DEFAULT_UNIX_SOCKET = f"http+unix://{ORBSTACK_SOCKET}"
+else:
+    DEFAULT_UNIX_SOCKET = "http+unix:///var/run/docker.sock"
+
 DEFAULT_NPIPE = 'npipe:////./pipe/docker_engine'
 
 BYTE_UNITS = {
diff --git a/docker/utils/utils.py b/docker/utils/utils.py
index f36a3afb..a7ddfcab 100644
--- a/docker/utils/utils.py
+++ b/docker/utils/utils.py
@@ -16,6 +16,7 @@ from ..constants import (
     DEFAULT_HTTP_HOST,
     DEFAULT_NPIPE,
     DEFAULT_UNIX_SOCKET,
+    ORBSTACK_SOCKET,
 )
 from ..tls import TLSConfig
 
@@ -235,6 +236,9 @@ def parse_host(addr, is_win32=False, tls=False):
     if not addr and is_win32:
         return DEFAULT_NPIPE
     if not addr or addr.strip() == 'unix://':
+        # If OrbStack socket exists, use it
+        if os.path.exists(ORBSTACK_SOCKET):
+            return f"http+unix://{ORBSTACK_SOCKET}"
         return DEFAULT_UNIX_SOCKET
 
     addr = addr.strip()