diff --git a/packages/grpc-js/src/client-interceptors.ts b/packages/grpc-js/src/client-interceptors.ts
index 52320b0b..d9c88f44 100644
--- a/packages/grpc-js/src/client-interceptors.ts
+++ b/packages/grpc-js/src/client-interceptors.ts
@@ -198,8 +198,6 @@ export interface InterceptingCallInterface {
   sendMessage(message: any): void;
   startRead(): void;
   halfClose(): void;
-
-  setCredentials(credentials: CallCredentials): void;
 }
 
 export class InterceptingCall implements InterceptingCallInterface {
@@ -337,9 +335,6 @@ export class InterceptingCall implements InterceptingCallInterface {
       }
     });
   }
-  setCredentials(credentials: CallCredentials): void {
-    this.nextCall.setCredentials(credentials);
-  }
 }
 
 function getCall(channel: Channel, path: string, options: CallOptions): Call {
@@ -371,9 +366,6 @@ class BaseInterceptingCall implements InterceptingCallInterface {
   getPeer(): string {
     return this.call.getPeer();
   }
-  setCredentials(credentials: CallCredentials): void {
-    this.call.setCredentials(credentials);
-  }
   // eslint-disable-next-line @typescript-eslint/no-explicit-any
   sendMessageWithContext(context: MessageContext, message: any): void {
     let serialized: Buffer;
diff --git a/packages/grpc-js/src/client.ts b/packages/grpc-js/src/client.ts
index d97c9fa3..f96f8fdf 100644
--- a/packages/grpc-js/src/client.ts
+++ b/packages/grpc-js/src/client.ts
@@ -321,9 +321,6 @@ export class Client {
      * before calling the CallInvocationTransformer, and we need to create the
      * call after that. */
     emitter.call = call;
-    if (callProperties.callOptions.credentials) {
-      call.setCredentials(callProperties.callOptions.credentials);
-    }
     let responseMessage: ResponseType | null = null;
     let receivedStatus = false;
     const callerStackError = new Error();
@@ -449,9 +446,6 @@ export class Client {
      * before calling the CallInvocationTransformer, and we need to create the
      * call after that. */
     emitter.call = call;
-    if (callProperties.callOptions.credentials) {
-      call.setCredentials(callProperties.callOptions.credentials);
-    }
     let responseMessage: ResponseType | null = null;
     let receivedStatus = false;
     const callerStackError = new Error();
@@ -582,9 +576,6 @@ export class Client {
      * before calling the CallInvocationTransformer, and we need to create the
      * call after that. */
     stream.call = call;
-    if (callProperties.callOptions.credentials) {
-      call.setCredentials(callProperties.callOptions.credentials);
-    }
     let receivedStatus = false;
     const callerStackError = new Error();
     call.start(callProperties.metadata, {
@@ -681,9 +672,6 @@ export class Client {
      * before calling the CallInvocationTransformer, and we need to create the
      * call after that. */
     stream.call = call;
-    if (callProperties.callOptions.credentials) {
-      call.setCredentials(callProperties.callOptions.credentials);
-    }
     let receivedStatus = false;
     const callerStackError = new Error();
     call.start(callProperties.metadata, {