diff --git a/tox.ini b/tox.ini
index 332662a5c..de7fe82ca 100644
--- a/tox.ini
+++ b/tox.ini
@@ -32,6 +32,10 @@ envlist =
     py3{5,6,7,8}-test-ext-aiohttp-client
     pypy3-test-ext-aiohttp-client
 
+    ; opentelemetry-ext-botocore
+    py3{6,7,8}-test-ext-botocore
+    pypy3-test-ext-botocore
+
     ; opentelemetry-ext-django
     py3{4,5,6,7,8}-test-ext-django
     pypy3-test-ext-django
@@ -172,6 +176,7 @@ changedir =
   test-ext-wsgi: ext/opentelemetry-ext-wsgi/tests
   test-ext-zipkin: ext/opentelemetry-ext-zipkin/tests
   test-ext-boto: ext/opentelemetry-ext-boto/tests
+  test-ext-botocore: ext/opentelemetry-ext-botocore/tests
   test-ext-flask: ext/opentelemetry-ext-flask/tests
   test-example-app: docs/examples/opentelemetry-example-app/tests
   test-getting-started: docs/getting_started/tests
@@ -205,6 +210,9 @@ commands_pre =
 
   flask: pip install {toxinidir}/ext/opentelemetry-ext-flask[test]
 
+  botocore: pip install {toxinidir}/opentelemetry-instrumentation
+  botocore: pip install {toxinidir}/ext/opentelemetry-ext-botocore[test]
+
   dbapi: pip install {toxinidir}/ext/opentelemetry-ext-dbapi[test]
 
   django: pip install {toxinidir}/ext/opentelemetry-ext-django[test]